Examine This Report on ubat gout farmasi
Examine This Report on ubat gout farmasi
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Tophi are smaller, chalk-colored, stone-like deposits of uric acid that gather underneath the pores and skin and therefore are most often found in pores and skin round the joints and on the outside of your ear.
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Allopurinol adalah salah satu ubat utama dalam terapi penurunan urate (ULT), yang bertujuan untuk mengurangkan pengeluaran asid urik dalam badan. Di Malaysia, allopurinol biasanya dimulakan sekurang-kurangnya empat minggu selepas serangan gout akut untuk mengelakkan keadaan menjadi lebih teruk.
Steroid seperti prednisolone juga digunakan sebagai rawatan alternatif bagi gout di Malaysia, terutamanya jika NSAIDs atau kolkisin tidak berkesan atau tidak boleh digunakan. Dalam kes-kes di mana kesakitan sangat teruk dan tidak dapat dikawal dengan ubat-ubatan lain, prednisolone pada dos thirty mg setiap hari selama lima hari boleh diberikan.
Penggunaan serentak dengan ubat tertentu yang meningkatkan risiko keracunan, seperti clarithromycin atau ketoconazole.
Kolkisin juga merupakan pilihan ubat yang biasa digunakan untuk menguruskan serangan gout. Ia sering digunakan bersama NSAIDs, terutamanya apabila pesakit tidak dapat mengambil dos NSAIDs yang besar. Kolkisin bertindak dengan mengurangkan keupayaan sel-sel darah putih untuk menyebabkan keradangan.
If you experience sudden, extreme ache inside of a joint, see your health care provider to get a diagnosis. Gout that's not taken care of could potentially cause irreversible joint damage, kidney stones as well as formation of tophi.
Selain osteoartritis, ubat NSAID juga biasa digunakan untuk merawat serangan gout, baik menghilangkan rasa sakit dan mengurangkan keradangan pada sendi.
Make sure you operate your medication checklist by your healthcare company or pharmacist to get safe. In distinction to NSAIDs and corticosteroids, colchicine may very well be continued prolonged-expression to avoid recurrent flares.
Based on the ACR guidelines, the goal of medication therapy is always to reduced uric acid levels to lower than 6 mg/dL. There's two different types of urate-decreasing medications:
Uric acid is really a waste product that is definitely shaped when purines - crucial substances located in protein along with other foods - are broken down. Under typical conditions, uric acid dissolves within the blood, passes from the kidneys, which is excreted in the urine. Not so in individuals with gout.
Vitamin D. Small vitamin D ranges are affiliated with large levels of uric acid, more info but far more exploration is needed to determine if supplementing is helpful.
Serangan gout dapat terjadi dengan cepat dan terus berulang dari masa ke masa, perlahan-lahan merosakkan tisu di kawasan keradangan dan boleh menjadi sangat menyakitkan. Hipertensi, kardiovaskular dan obesiti adalah faktor risiko bagi penyakit gout.
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